Enjoy Life health & wellbeing
Enjoy Life health & wellbeing
Enjoy Life health & wellbeing
Enjoy Life health & wellbeing


Research on OPC and Oedema


Oedema is the swelling that occurs in and around injured tissue. From a simple sprained ankle to major surgery, oedema can affect the body significantly.

OPC has been researched in at least three types of oedema:
  • in sport injuries
  • in plastic surgery (face lifting)
  • in operational intervention of breast cancer

  • Sports Injuries

    Most sport injuries result in oedema. This usually involves ripped capillaries that are the result of torn muscles, sprains, fractures, twisting and whiplash injuries. Such an injury is painful and uncomfortable for anyone. However, the achievement-oriented sportsperson suffers most from this. They are often confronted with a loss in their physical condition due to the fact that they cannot train to compete.

    19831 – The effect of OPC was measured on forty soccer players that sustained an injury.

    Immediately after the injury (day one) they took 400mg of OPC. On days two through eight, they took 300mg per day and on days nine and ten they took 200mg per day. On the tenth day oedema appeared to a lesser extent in the OPC group than in the control group that did not receive OPC. In some cases, the oedema disappeared completely. The researchers also concluded that the overall condition of the OPC group was better than that of the control group.1

    Plastic Surgery

    19842 – A test was conducted on thirty-two patients to establish whether, after a face-lift, less oedema would occur with the ingestion of OPC. From five days before until six days after the operation, 300mg of OPC per day were given to half of the patients while the other half received no OPC. The operations were performed by the same surgeon, with the same technique and under the same sort of anaesthesia.

    The difference between the two groups was significant. The most important criterion in assessing the result was the disappearance of oedema. The OPC group fulfils this criterion on the twelfth day (11.4 days), while the control group needed sixteen days (15.8 days) to achieve the same result. 2

    Cancer Surgery 19893 – After the surgical treatment of breast cancer, oedema sometimes occurs in the arms. This is often accompanied by pain, tension in the skin and difficulties in shoulder and arm movements. Researchers reported that they tested the effects of OPC, with regard to this problem, on a group of sixty-three women of whom thirty-three received OPC and thirty received a placebo.

    During the first six weeks of the research the placebo was just as effective as OPC, but after a longer period of time (six months in total), the placebo effect disappeared and it became evident that the positive effects of OPC endured longer.3

    1. Parienti, J. & Parienti-Amsellem, J. (1983). Les oedèmes post-traumatiques chez le sportif: essai contrôlé de l’Endotélon. Gaz. Med. De France – 90, no 3 du 21 Jan 1983.(return)
    2. Baruch, J. (1984). Effet de l’Endotélon dans les oedèmas post-chirurgicaux. Résultats d’une étude en double aveugle contre placebo sur trente-deux patients. Ann. Chir. Plast Esthét 1984, vol. XXIX, no 4.(return)
    3. Pecking, A., Desprez-Curely, J. & Megret, G. (1989). Oligomères procyanidoliques (Endotélon) dans le traitement des lymphoedèmes post-thérepeutiques des members supérieurs. Symposium Satellite, Congrès International d’Angiologie, Toulouse (France), 4-7 Octobre 1989.(to the top)

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    Enjoy Life health & wellbeing
    Enjoy Life health & wellbeing